Buy Xeljanz for patients suffering from rheumatoid arthritis. The medication, which has the generic name of tofacitnib, is also prescribed for those who have active psoriatic arthritis, as well as other ailments.
Who benefits the most from Xeljanz
This medicine is part of the antirheumatics class of drugs, and patients with some type of arthritis are those who are usually recommended this medication.
Ailments Treated with Xeljanz
These are some of the ailments that Xeljanz is capable of treating:
- Rheumatoid arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Ulcerative colitis
- Juvenile idiopathic arthritis
How does Xeljanz work?
Xeljanz contains the active ingredient tofacitinib, which treats patients by blocking the action of Janus kinases, which are a kind of enzyme. These enzymes are integral in the process of inflammation commonly observed in patients with various kinds of arthritis, including rheumatoid, psoriatic, or juvenile idiopathic. This kind of inflammation can also be seen in patients with ulcerative colitis, and because of Xeljanz So by blocking that enzyme, the treatment effectively lessens the inflammation, as well as other symptoms of the disease.
Xeljanz can be used with another medicine called methotrexate, and when one or more drugs known as disease-modifying anti-rheumatic drugs have not worked, then the two aforementioned solutions are sometimes next in line.
For rheumatoid arthritis, the usual dosage for adults as a monotherapy, or even as a combination with disease-modifying anti-rheumatic drugs that are non-biologic is 5mg orally twice a day for immediate release, and 11mg orally once a day for extended release. It should be noted though that the drug should not be initiated if absolute lymphocyte count is less than 500 cells/mm³, if hemoglobin is below 9 g/dL, or if absolute neutrophil count is less than 1000 cells/mm³.
For more information on dosing, please refer to the product leaflet.
How long does Xeljanz last?
In as little as two weeks, clinical studies have proven that reduced RA joint pain can be observed. Generally speaking, though, the medication can take three to six months to work according to the manufacturer.
Patients with hypersensitivities to any of Xeljanz’s components should avoid it. Those who have active tuberculosis, and other serious or opportunistic infections should also avoid the product. Those who are pregnant or lactating, or those with severe hepatic impairment are also contraindicated. For a full list, please refer to package insert.
Other Side Effects
These are signs of infections and if the patient has them, they should immediately call the doctor
- Sudden shortness of breath
- Nausea, vomiting, cold sweat
- Weakness on one side of the body
- Slurred speech, drooping in one side of the mouth
Common side effects include:
- Cold symptoms
- Increase blood pressure
For a full list, please check the package leaflet.
Patients who are undergoing this treatment should avoid receiving any live vaccines, which include but are not limited to mumps, measles, rubella, rotavirus, yellow fever, typhoid, shingles, and chickenpox.
Cost of Xeljanz
30 tablets each with 5mg of this medication will average for around $2528.
In clinical studies, Xeljanz has shown the ability to significantly reduce joint swelling and pain. It is also effective at improving the joint’s movement as well as slowing down any further joint damage, and in one study where Xeljanz was used alone, it proved more effective than methotrexate.
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