GlaxoSmithKline (Benlysta) | About the Brand



GSK plc, is a multination pharmaceutical company that has its headquarters in London, England. Primarily a British group, it was established via merger of the Glaxo Wellcome and SMithKline Beecham, and was the sixth largest pharmaceutical company as of 2019 according to Forbes. The company is known to be the first developer of the malaria vaccine, and their legacy products include several that are listed in the World Health Organization’s list of essential medicines; these include amoxicillin, pyrimethamine, zidovudine, and mercaptopurine.  

One of the products in their vast portfolio is Benlysta, a human monoclonal antibody which is used as a treatment for lupus nephritis. It is a kind of protein that was made to specifically latch onto one type of substance in the body, in this case B-lymphocyte stimulator or BLyS. By having Benlysta latch onto the BLyS, it prevents that stimulator from latching onto and prolonging the survival of B cells, which are cells that can produce autoantibodies, or antibodies that target and attack the body’s own healthy tissue.  


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